Studies on the Streptomyces Antibiotic, Cycloheximide. XII. N-Mercuricycloheximides.
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چکیده
منابع مشابه
Cycloheximide production by Streptomyces griseus: control mechanisms of cycloheximide biosynthesis.
Cycloheximide accumulation in a fermentation medium has been shown to be the product of the balance between synthesis and degradation of this antibiotic. Glucose has been shown to prevent cycloheximide degradation. Cycloheximide has been shown to interfere with its own synthesis probably due to feedback inhibition. Approaches for increasing cycloheximide titers in the light of these findings ar...
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During the course of screening for new antibiotics, a Streptomyces strain A-14317 isolated from a soil sample collected at Ito-gun, Wakayama Prefecture was found to produce an antibiotic AB-74,x' related to destomycin C, together with neomycins A, B, C and hygromycin B. On the basis of morphological and physiological characteristics of strain A-14317, the organism was considered a new species a...
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Since the isolation of streptothricin by Waksman and Woodruff in 1942 from a strain of Streptomyces lavendulae, numerous reports have appeared concerning the ability of different actinomycetes to produce this antibiotic or closely related compounds. In most of the antibiotic screening programs, streptothricin and streptothricinlike substances are among the first to be commonly encountered as pr...
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The biosynthesis of saframycin A, a heterocyclic quinone antitumor antibiotic isolated from Streptomyces lavendulae 314, was studied by feeding experiments with 14C and 13C precursors. Highly increased production of saframycin A and prolongation of the maximum production period of saframycin A were attained by constant pH control of the culture and by addition of chloramphenicol to the culture....
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Numerous antibiotics have been obtained from the broth culture of streptomyces, however, none of the antibiotics consisting of carbon, hydrogen, chlorine and oxygen has yet been found. A strain recently isolated from the soil produces an antibiotic which inhibits the growth of Gram positive bacteria. This antibiotic is a new one, because it consists of carbon, hydrogen, chlorine and oxygen. The...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1961
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.9.515